Detalhe da pesquisa
1.
RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention.
PLoS Biol
; 22(2): e3002527, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38422113
2.
A Helicase Unwinds Hexanucleotide Repeat RNA G-Quadruplexes and Facilitates Repeat-Associated Non-AUG Translation.
J Am Chem Soc
; 143(19): 7368-7379, 2021 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33855846
3.
Dancing muscles: the value of real-time ultrasound evaluation of muscle in myositis and mimics.
Rheumatology (Oxford)
; 60(8): e275-e276, 2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33502477
4.
DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD.
Exp Neurol
; 376: 114768, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38556190
5.
Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes.
bioRxiv
; 2024 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37577513
6.
RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention.
bioRxiv
; 2023 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37609278
7.
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration.
Nat Neurosci
; 26(8): 1328-1338, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37365312
8.
Elevated nuclear TDP-43 induces constitutive exon skipping.
bioRxiv
; 2023 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37215013
9.
Adult intestinal colonization botulism mimicking brain death.
Muscle Nerve
; 56(4): E27-E28, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28500638
10.
Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD.
Neurotherapeutics
; 19(4): 1061-1084, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35790708
11.
Nuclear RNA binding regulates TDP-43 nuclear localization and passive nuclear export.
Cell Rep
; 40(3): 111106, 2022 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35858577
12.
Nuclear Transport Assays in Permeabilized Mouse Cortical Neurons.
J Vis Exp
; (173)2021 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34309603
13.
UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
Cell Rep
; 34(13): 108925, 2021 03 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33789100
14.
Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD.
Nat Commun
; 12(1): 4908, 2021 08 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34389711
15.
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
iScience
; 24(11): 103221, 2021 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34746695
16.
C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import.
Elife
; 92020 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32119645
17.
G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD.
Neuron
; 107(6): 1124-1140.e11, 2020 09 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32673563
18.
Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Neuron
; 105(4): 645-662.e11, 2020 02 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31831332
19.
Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal.
Exp Neurol
; 318: 251-257, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31082391
20.
CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
Neuron
; 104(5): 885-898.e8, 2019 12 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31587919